Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 13/20 | 0.50 |
| ▸ | PLAU | P00749 | 12/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27962643 | 0.88 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTPOLBHTT | |
| SCHEMBL8558497 | 0.82 | GAA (0.61) | HPNPLAUALDH1A1NQO2F2 | |
| SCHEMBL9029174 | 0.81 | ALDH1A1 (0.45) | PLAUALDH1A1F2MRGPRX1MAPT | |
| SCHEMBL8127463 | 0.81 | CYP2D6 (0.55) | HPNPLAUALDH1A1NQO2F2 | |
| SCHEMBL27962645 | 0.79 | KMT2A (0.60) | ALDH1A1LMNAMAPTPOLBHTT | |
| SCHEMBL776957 | 0.79 | HSD11B1 (0.62) | ALDH1A1LMNAMAPTPOLBHTT | |
| SCHEMBL27962683 | 0.79 | RECQL (0.62) | ALDH1A1LMNAMAPTPOLBHTT | |
| 4-Methylbenzimidamide SCHEMBL1050355 | 0.78 | NQO2 (0.51) | HPNPLAUALDH1A1NQO2F2 | |
| SCHEMBL9805301 | 0.78 | CA1 (0.54) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8554901 | 0.78 | MAPT (0.54) | HPNPLAUALDH1A1F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |