Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 9/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RARA | P10276 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL11519115 | 1.00 | TP53 (0.57) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL27832793 | 1.00 | TP53 (0.57) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL15015693 | 1.00 | TP53 (0.57) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL28198649 | 0.92 | RARB (0.53) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL3842017 | 0.91 | TP53 (0.53) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL28502502 | 0.86 | TP53 (0.71) | TP53TSHRRARBPLA2G4BMEN1 | |
| Tetradecane SCHEMBL30605685 | 0.86 | TP53 (0.71) | TP53TSHRRARBPLA2G4BMEN1 | |
| Dodecane SCHEMBL9354416 | 0.86 | TP53 (0.71) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL28142960 | 0.86 | TP53 (0.71) | TP53TSHRRARBPLA2G4BMEN1 | |
| Terephthalic Acid SCHEMBL9016064 | 0.86 | GPR84 (0.72) | TP53TSHRRARBPLA2G4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019078585-A1 | NON-REACTIVE FLUORINE-BASED COMPOUND AND PHOTOPOLYMERIZABLE COMPOSITION INCLUDING SAME | 주식회사 엘지화학 | 2019-04-25 | — | — | WO | disclosed |
| CN-1134495-C | Flame-retardant resin compsn. and moldings | 大庆油田有限责任公司 | 2004-01-14 | — | — | CN | disclosed |
| CN-1197466-A | Flame-retardant resin compsn. and moldings | TORAY INDUSTRIES (JP) | 1998-10-28 | — | — | CN | disclosed |
| EP-0187176-B1 | METAL-PLATED MOLDING | TORAY INDUSTRIES, INC. (JP) | 1991-03-20 | — | — | EP | disclosed |
| US-4664983-A | METAL-PLATED | TORAY INDUSTRIES INC. (JP) | 1987-05-12 | — | — | US | disclosed |