⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27925027 | 1.00 | — | — | |
| SCHEMBL27533247 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28147292 | 0.98 | ADH1B (0.41) | — | |
| Hydrochloric Acid SCHEMBL28261599 | 0.98 | — | — | |
| SCHEMBL983031 | 0.93 | — | — | |
| SCHEMBL28199409 | 0.91 | ADH1B (0.48) | — | |
| Hydrochloric Acid SCHEMBL28168897 | 0.91 | ADH1B (0.44) | — | |
| SCHEMBL981043 | 0.91 | ADH1B (0.48) | — | |
| Trifluoroacetic Acid SCHEMBL28287695 | 0.84 | MEN1 (0.33) | — | |
| SCHEMBL3526133 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004779-A | Chemical synthesis method of proline | 四川天华化工集团股份有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-115611883-A | PI3K alpha inhibitor with bicyclic structure and preparation method and application thereof | 生物岛实验室 | 2023-01-17 | — | — | CN | claimed |
| CN-112174870-A | Preparation method and medicinal application of (R) -1-alkanoyl-2-substituted pyrrolidine-2-formamide | 蔡霈 | 2021-01-05 | — | — | CN | claimed |
| CN-110325509-A | Functional derivative compound of alanine and proline amino acid and pharmaceutical composition containing same | 阿米蒂比奥有限公司 | 2019-10-11 | — | — | CN | claimed |
| CN-106661017-B | Bicyclic or tricyclic heterocyclic compounds | 田边三菱制药株式会社 | 2019-09-24 | — | — | CN | claimed |
| CN-110240629-A | Protein degradation targets BCR-ABL compound and its antitumor application thereof | 上海科技大学 | 2019-09-17 | — | — | CN | claimed |
| CN-110240591-A | Proline derivative and its preparation method and application | 天津药物研究院有限公司 | 2019-09-17 | — | — | CN | claimed |
| CN-106660955-B | Cyclohexene derivative, preparation method and the pharmaceutical composition for being used to prevent or treat metabolic disease comprising it as active constituent | 现代药品株式会社 | 2019-08-23 | — | — | CN | claimed |
| CN-110036006-A | The preparation and use of pyrimidone derivatives | 癌症研究科技有限公司 | 2019-07-19 | — | — | CN | claimed |
| CN-110028494-A | Amide derivatives, its stereoisomer or its pharmaceutically acceptable salt and the pharmaceutical composition comprising it | 株式会社钟根堂 | 2019-07-19 | — | — | CN | claimed |
| US-6837908-B2 | 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2005-01-04 | — | — | US | claimed |
| EP-1484049-A1 | Imidazole compounds and their use for dyeing of keratinous fibres | L'OREAL (FR) | 2004-12-08 | — | — | EP | claimed |
| EP-1459732-A1 | Dye composition comprising at least one heterocyclic oxidation base and at least one 2,3,5-triaminopyridine as coupler | L'OREAL (FR) | 2004-09-22 | — | — | EP | claimed |
| EP-1457199-A1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-15 | — | — | EP | claimed |
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2003-12-11 | — | — | US | claimed |
| US-20030163876-A1 | Novel 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2003-09-04 | — | — | US | claimed |
| EP-1336606-A1 | 6-Alkoxy-2,3-diaminopyridine couplers for dying keratin fibers | L'OREAL (FR) | 2003-08-20 | — | — | EP | claimed |
| EP-1312606-A1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | L'OREAL (FR) | 2003-05-21 | — | — | EP | claimed |
| CN-1419541-A | Pharmaceutically active pyrrolidine derivatives as BAX inhibitors | APPLIED RES SYSTEMS AKS HOLDIN (NL) | 2003-05-21 | — | — | CN | claimed |
| CN-1404479-A | 1, 3-dihydro-2H-indol-2-one derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2003-03-19 | — | — | CN | claimed |