⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981043 | 0.98 | ADH1B (0.48) | — | |
| Hydrochloric Acid SCHEMBL28168897 | 0.98 | ADH1B (0.44) | — | |
| SCHEMBL28199409 | 0.98 | ADH1B (0.48) | — | |
| SCHEMBL980593 | 0.93 | — | — | |
| SCHEMBL27533247 | 0.93 | — | — | |
| SCHEMBL27925027 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL28147292 | 0.91 | ADH1B (0.41) | — | |
| Hydrochloric Acid SCHEMBL28261599 | 0.91 | — | — | |
| SCHEMBL3526133 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL29288170 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117630247-A | Method for simultaneously determining multiple impurities in piperidine-4-formamide | 上海方予健康医药科技有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-112778067-B | Method for synthesizing thioamide compound by catalyzing 1,2, 3-thiadiazole compound and amine with copper | 华南理工大学 | 2022-05-24 | — | — | CN | claimed |
| CN-112778067-A | Method for synthesizing thioamide compound by using copper to catalyze 1,2, 3-thiodiazole compound and amine | 华南理工大学 | 2021-05-11 | — | — | CN | claimed |
| CN-109503415-A | A kind of tranilast co-crystal thereof, preparation method and application | 药大制药有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-109503465-A | A kind of preparation of Ropivacaine HCL intermediate and purification process | 河北品制药股份有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-109311819-A | Isoquinolin -3- base benzamide type and its preparation and its purposes | 萨穆梅德有限公司 | 2019-02-05 | — | — | CN | claimed |
| CN-105517993-B | Aryl amide kinase inhibitors | 百时美施贵宝公司 | 2018-07-13 | — | — | CN | claimed |
| CN-108191837-A | PI3K α/mTOR bidifly enzyme inhibitors and its pharmaceutical composition and application | 贵州医科大学 | 2018-06-22 | — | — | CN | claimed |
| CN-104364246-B | Piperidine derivatives useful as GPR119 agonists | 株式会社钟根堂 | 2018-05-22 | — | — | CN | claimed |
| CN-107991404-A | A kind of detection method of (2S, 5R)-benzyloxy anilinic piperidines -2- formamides | 中山奕安泰医药科技有限公司 | 2018-05-04 | — | — | CN | claimed |
| US-20050011019-A1 | Novel imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2005-01-20 | — | — | US | claimed |
| EP-1498109-A1 | Furan derivatives and dyeing composition comprising a furan derivative as coupler | L'OREAL (FR) | 2005-01-19 | — | — | EP | claimed |
| US-6837908-B2 | 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2005-01-04 | — | — | US | claimed |
| EP-1484049-A1 | Imidazole compounds and their use for dyeing of keratinous fibres | L'OREAL (FR) | 2004-12-08 | — | — | EP | claimed |
| EP-1459732-A1 | Dye composition comprising at least one heterocyclic oxidation base and at least one 2,3,5-triaminopyridine as coupler | L'OREAL (FR) | 2004-09-22 | — | — | EP | claimed |
| EP-1457199-A1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-15 | — | — | EP | claimed |
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2003-12-11 | — | — | US | claimed |
| US-20030163876-A1 | Novel 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2003-09-04 | — | — | US | claimed |
| EP-1336606-A1 | 6-Alkoxy-2,3-diaminopyridine couplers for dying keratin fibers | L'OREAL (FR) | 2003-08-20 | — | — | EP | claimed |
| EP-1312606-A1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | L'OREAL (FR) | 2003-05-21 | — | — | EP | claimed |