Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172164 | 0.86 | LMNA (0.74) | LMNAMEN1KMT2AABCC4PKM | |
| Nalidixic Acid SCHEMBL21736 | 0.85 | KMT2A (1.00) | LMNAMEN1KMT2AABCC4PKM | |
| Nalidixic Acid SCHEMBL7878858 | 0.85 | KMT2A (1.00) | LMNAMEN1KMT2AABCC4PKM | |
| Nalidixic Acid SCHEMBL29367723 | 0.85 | KMT2A (1.00) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL11791745 | 0.85 | LMNA (0.76) | LMNAMEN1KMT2AABCC4PKM | |
| Nalidixic Acid SCHEMBL4766415 | 0.84 | KMT2A (0.97) | LMNAMEN1KMT2AABCC4PKM | |
| Nalidixic Acid SCHEMBL9743582 | 0.84 | KMT2A (0.97) | LMNAMEN1KMT2AABCC4PKM | |
| Nalidixic Acid SCHEMBL27256972 | 0.84 | KMT2A (0.97) | LMNAMEN1KMT2AABCC4PKM | |
| Nalidixic Acid SCHEMBL950987 | 0.84 | KMT2A (0.97) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL10278384 | 0.84 | LMNA (0.74) | LMNAMEN1KMT2AABCC4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077429-A | 7-AMINO-1-CYCLOPROPYL-4-OXO-1,4-DIHYDRO-QUINOLINE- AND NAPHTHYRIDINE-3-CARBOXYLIC ACIDS, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS CONTAINING THESE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | disclosed |
| US-4670444-A | 7-amino-1-cyclopropyl-4-oxo-1, 4-dihydro-quinoline-and naphthyridine-3-carboxylic acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-02 | — | — | US | disclosed |
| US-4620007-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-28 | — | — | US | disclosed |
| US-4552882-A | 7-(1-Pyrrolyl) derivatives of 1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids and 1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids and their use as antimicrobial agents | PROVESAN, SA (CH) | 1985-11-12 | — | — | US | disclosed |