Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805935 | 0.86 | LMNA (0.74) | LMNAKMT2AMEN1ABCC4PKM | |
| Nalidixic Acid SCHEMBL7878858 | 0.85 | KMT2A (1.00) | LMNAKMT2AMEN1ABCC4PKM | |
| SCHEMBL11791745 | 0.85 | LMNA (0.76) | LMNAKMT2AMEN1ABCC4PKM | |
| Nalidixic Acid SCHEMBL21736 | 0.85 | KMT2A (1.00) | LMNAKMT2AMEN1ABCC4PKM | |
| Nalidixic Acid SCHEMBL29367723 | 0.85 | KMT2A (1.00) | LMNAKMT2AMEN1ABCC4PKM | |
| SCHEMBL8703572 | 0.85 | ALDH1A1 (0.62) | LMNAKMT2AMEN1ABCC4PKM | |
| SCHEMBL10278384 | 0.84 | LMNA (0.74) | LMNAKMT2AMEN1ABCC4PKM | |
| Nalidixic Acid SCHEMBL950987 | 0.84 | KMT2A (0.97) | LMNAKMT2AMEN1ABCC4PKM | |
| Nalidixic Acid SCHEMBL4766415 | 0.84 | KMT2A (0.97) | LMNAKMT2AMEN1ABCC4PKM | |
| Nalidixic Acid SCHEMBL27256972 | 0.84 | KMT2A (0.97) | LMNAKMT2AMEN1ABCC4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776431-B1 | 2-OXO-OXAZOLIDIN-3,5-DIYL ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2016-05-04 | — | — | EP | disclosed |
| US-9079922-B2 | 2-oxo-oxazolidin-3,5-diyl antibiotic derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2015-07-14 | — | — | US | disclosed |
| US-20150051188-A1 | 2-OXO-OXAZOLIDIN-3,5-DIYL ANTIBIOTIC DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2015-02-19 | — | — | US | disclosed |
| EP-2776431-A1 | 2-OXO-OXAZOLIDIN-3,5-DIYL ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013068948-A1 | 2-OXO-OXAZOLIDIN-3,5-DIYL ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |
| US-20090062218-A1 | MACROLONE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-03-05 | — | — | US | disclosed |
| US-4017622-A | BACTERICIDES | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051188-A1 | 2-OXO-OXAZOLIDIN-3,5-DIYL ANTIBIOTIC DERIVATIVES | OXA1L, PYM1, MRPL21 | LMNA 1198/4885KMT2A 1930/4885MEN1 538/4885 |
| US-20090062218-A1 | MACROLONE COMPOUNDS | CYP51A1, MRPL21, MYD88 | LMNA 1055/4885KMT2A 3931/4885MEN1 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.