Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.62 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.61 |
| ▸ | ITGAL | P20701 | 1/20 | 0.61 |
| ▸ | TACR1 | P25103 | 1/20 | 0.60 |
| ▸ | BRS3 | P32247 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346003 | 1.00 | KCNT1 (0.62) | KCNT1MMP2MMP9ITGB2ICAM1 | |
| SCHEMBL8705016 | 0.92 | KCNT1 (0.69) | KCNT1MMP2MMP9ITGB2ICAM1 | |
| SCHEMBL900917 | 0.92 | KCNT1 (0.69) | KCNT1MMP2MMP9ITGB2ICAM1 | |
| SCHEMBL9583736 | 0.92 | KCNT1 (0.69) | KCNT1MMP2MMP9ITGB2ICAM1 | |
| SCHEMBL29810269 | 0.92 | KCNT1 (0.69) | KCNT1MMP2MMP9ITGB2ICAM1 | |
| SCHEMBL24122265 | 0.89 | ACE (0.64) | ACE | |
| SCHEMBL11349644 | 0.88 | MAPT (0.61) | KCNT1MMP2MMP9TACR1BRS3 | |
| SCHEMBL22654181 | 0.86 | ALOX15 (0.65) | MMP2MMP9ITGB2ICAM1ITGAL | |
| SCHEMBL150050 | 0.86 | ALOX15 (0.65) | MMP2MMP9ITGB2ICAM1ITGAL | |
| SCHEMBL29773000 | 0.86 | ALOX15 (0.65) | MMP2MMP9ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422181-A1 | METHOD AND MEANS FOR INDUCING, RESP., PREVENTING CONSTRICTION OF THE PUPIL IN THE EYE | Kabi Pharmacia AB (SE) | 1991-04-17 | — | — | EP | disclosed |
| WO-1990011773-A1 | METHOD AND MEANS FOR INDUCING, RESP., PREVENTING CONSTRICTION OF THE PUPIL IN THE EYE | PHARMACIA AB (SE) | 1990-10-18 | — | — | WO | disclosed |