Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 8/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | EBP | Q15125 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760171 | 0.90 | ESRRG (0.43) | KMT2AMEN1MAPTKDM4EHTT | |
| SCHEMBL11278094 | 0.77 | ALDH1A1 (0.44) | KCNH2ADRA2AKMT2AADRA2BHTR2A | |
| SCHEMBL19041280 | 0.77 | CES2 (0.53) | KCNH2ADRA2AADRA2BHTR2APGR | |
| SCHEMBL11278110 | 0.77 | ALDH1A1 (0.44) | KCNH2ADRA2AKMT2AADRA2BHTR2A | |
| SCHEMBL19040950 | 0.77 | ALDH1A1 (0.44) | KCNH2ADRA2AKMT2AADRA2BHTR2A | |
| SCHEMBL1553459 | 0.75 | ESR1 (0.39) | PTGS2ESR1KMT2AADORA3MEN1 | |
| SCHEMBL1553457 | 0.75 | ESR1 (0.39) | PTGS2ESR1KMT2AADORA3MEN1 | |
| SCHEMBL11719533 | 0.75 | CES2 (0.46) | KCNH2ADRA2AADRA2BHTR2APGR | |
| SCHEMBL11719526 | 0.75 | CES2 (0.46) | KCNH2ADRA2AADRA2BHTR2APGR | |
| SCHEMBL12422795 | 0.74 | ALDH1A1 (0.40) | KCNH2ADRA2AKMT2ASIGMAR1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063126-A | Charge generating layer containing an n- and p-type dye and a charge transporting layer on a conductive substrate; weight ra tio; red copying | MITA INDUSTRIAL CO., LTD. (JP) | 1991-11-05 | — | — | US | disclosed |
| EP-0369765-A2 | Electrophotographic photosensitive material | MITA INDUSTRIAL CO. LTD. (JP) | 1990-05-23 | — | — | EP | disclosed |