Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | NQO2 | P16083 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806371 | 1.00 | ESR1 (0.55) | ESR1ESR2TP53MAPTSMN1; SMN2 | |
| SCHEMBL13808874 | 0.87 | ESR1 (0.47) | ESR1ESR2TP53MAPTSMN1; SMN2 | |
| SCHEMBL726321 | 0.87 | ESR1 (0.58) | ESR1ESR2PTGS2NQO2PTGS1 | |
| SCHEMBL726320 | 0.87 | ESR1 (0.58) | ESR1ESR2PTGS2NQO2PTGS1 | |
| SCHEMBL1225178 | 0.87 | ESR1 (0.58) | ESR1ESR2PTGS2NQO2PTGS1 | |
| Bicarbonate SCHEMBL27941948 | 0.86 | SMN1; SMN2 (0.57) | ESR1ESR2TP53MAPTSMN1; SMN2 | |
| SCHEMBL8712456 | 0.83 | ESR1 (0.80) | ESR1ESR2PTGS2NQO2PTGS1 | |
| SCHEMBL8712455 | 0.83 | ESR1 (0.80) | ESR1ESR2PTGS2NQO2PTGS1 | |
| SCHEMBL6547576 | 0.83 | ESR1 (0.55) | ESR1ESR2MAPTPTGS2NQO2 | |
| SCHEMBL7803180 | 0.82 | ESR1 (0.64) | ESR1ESR2MAPTPTGS2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734824-A | MONOOLEFIN OR DIOLEFIN HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-03-29 | — | — | US | claimed |
| EP-3597673-B1 | PHOTOCROSSLINKABLE POLYMER, INSULATING FILM, PLANARIZATION FILM, LYOPHILIC/LIQUID REPELLENT PATTERNED FILM, AND ORGANIC FIELD EFFECT TRANSISTOR DEVICE COMPRISING SAME | TOSOH CORP (JP) | 2023-06-07 | — | — | EP | disclosed |
| US-4994539-A | Ethylene-unsaturated aromatic copolymer | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0180771-B1 | METHOD FOR IMPROVING IMPULSE BREAKDOWN STRENGTH OF ELECTRICALLY INSULATING MATERIALS | Nippon Petrochemicals Co., Ltd. (JP) | 1989-08-02 | — | — | EP | disclosed |
| US-4734824-A | MONOOLEFIN OR DIOLEFIN HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0154993-B1 | ELECTRICAL INSULATING OIL AND ELECTRICAL APPLIANCES IMPREGNATED WITH THE SAME | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |
| US-4621302-A | MONO-OR DIOLEFIN HAVING THREE CONDENSED OR NON-CONDENSED AROMATIC RINGS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0180771-A1 | Method for improving impulse breakdown strength of electrically insulating materials | Nippon Petrochemicals Co., Ltd. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0155214-A2 | 2-sulfamoyl-1H-indole derivatives for the treatment of elevated intraocular pressure | MERCK & CO. INC. (US) | 1985-09-18 | — | — | EP | disclosed |