Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TTR | P02766 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806500 | 0.86 | MAPT (0.52) | MEN1PTGS2AKR1C3KMT2ATTR | |
| SCHEMBL9806482 | 0.82 | AKR1C3 (0.50) | MEN1PTGS2AKR1C3KMT2ATTR | |
| SCHEMBL11186246 | 0.79 | MEN1 (0.71) | MEN1PTGS2AKR1C3KMT2ATTR | |
| SCHEMBL1186465 | 0.79 | FABP4 (0.59) | MEN1PTGS2AKR1C3KMT2ATTR | |
| Clofenamic Acid SCHEMBL29900200 | 0.79 | PBRM1 (0.73) | MEN1PTGS2AKR1C3KMT2ATTR | |
| Clofenamic Acid SCHEMBL1477650 | 0.79 | PBRM1 (0.73) | MEN1PTGS2AKR1C3KMT2ATTR | |
| SCHEMBL9806562 | 0.78 | AKR1C3 (0.49) | MEN1PTGS2AKR1C3KMT2ATTR | |
| SCHEMBL638961 | 0.77 | PBRM1 (0.48) | MEN1PTGS2AKR1C3KMT2ATTR | |
| SCHEMBL22662676 | 0.76 | FABP4 (0.66) | MEN1PTGS2AKR1C3KMT2ATTR | |
| SCHEMBL30320327 | 0.76 | FABP4 (0.80) | MEN1PTGS2AKR1C3KMT2ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | disclosed |