Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806523 | 0.87 | MAPT (0.50) | MAPTALOX15PTGS2KDM4EKMT2A | |
| SCHEMBL9806493 | 0.86 | MEN1 (0.57) | MAPTPTGS2KMT2AHPGDTDP1 | |
| SCHEMBL9806508 | 0.85 | MAPT (0.54) | MAPTALOX15PTGS2KDM4EKMT2A | |
| SCHEMBL9551829 | 0.83 | PTGS2 (0.46) | MAPTALOX15PTGS2KDM4EKMT2A | |
| SCHEMBL19065779 | 0.79 | MAPT (0.79) | MAPTALOX15PTGS2KDM4EKMT2A | |
| SCHEMBL16843152 | 0.77 | KDM4E (0.60) | MAPTALOX15KDM4EKMT2AGAA | |
| SCHEMBL9806492 | 0.77 | MAPT (0.54) | MAPTALOX15PTGS2KDM4EKMT2A | |
| SCHEMBL9806587 | 0.75 | MAPT (0.51) | MAPTALOX15PTGS2KDM4EKMT2A | |
| SCHEMBL9806519 | 0.75 | MAPT (0.51) | MAPTALOX15PTGS2KDM4EKMT2A | |
| SCHEMBL13465152 | 0.74 | MT-CO2 (0.73) | MAPTALOX15PTGS2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | disclosed |