Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.59 |
| ▸ | TTR | P02766 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | FABP2 | P12104 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806512 | 0.89 | PTGS2 (0.61) | FTOTTRPTGS2MEN1AKR1B10 | |
| SCHEMBL9806482 | 0.85 | AKR1C3 (0.50) | FTOTTRPTGS2MEN1AKR1B10 | |
| SCHEMBL9806521 | 0.81 | FTO (0.48) | FTOTTRPTGS2MEN1AKR1B10 | |
| SCHEMBL7350437 | 0.79 | PTGS2 (0.55) | FTOTTRPTGS2MEN1AKR1B10 | |
| SCHEMBL9806486 | 0.77 | CLCN2 (0.73) | FTOTTRPTGS2MEN1AKR1B10 | |
| Meclofenamic Acid SCHEMBL29379636 | 0.75 | PTGS2 (1.00) | FTOTTRPTGS2MEN1AKR1B10 | |
| Meclofenamic Acid SCHEMBL106 | 0.75 | PTGS2 (1.00) | FTOTTRPTGS2MEN1AKR1B10 | |
| Meclofenamic Acid SCHEMBL11543781 | 0.75 | PTGS2 (1.00) | FTOTTRPTGS2MEN1AKR1B10 | |
| Meclofenamic Acid SCHEMBL29373906 | 0.75 | PTGS2 (1.00) | FTOTTRPTGS2MEN1AKR1B10 | |
| SCHEMBL24021566 | 0.74 | CLCN2 (1.00) | FTOTTRPTGS2MEN1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | claimed |