Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 16/20 | 0.65 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9082964 | 0.95 | FDPS (0.67) | FDPSGGPS1PDE3AHRH3LMNA | |
| SCHEMBL9084725 | 0.92 | FDPS (0.71) | FDPSGGPS1PDE3AHRH3LMNA | |
| SCHEMBL6890158 | 0.87 | FDPS (0.63) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL8703776 | 0.79 | FDPS (1.00) | FDPSPDE3AHRH3LMNAADRB3 | |
| SCHEMBL8706931 | 0.78 | FDPS (0.97) | FDPSPDE3AHRH3LMNAADRB3 | |
| SCHEMBL9806694 | 0.74 | FDPS (0.90) | FDPSPDE3ALMNAADRB3PDE4D | |
| Hydrochloric Acid SCHEMBL8465225 | 0.73 | FDPS (0.57) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL9794690 | 0.73 | FDPS (0.65) | FDPSLMNA | |
| SCHEMBL8706934 | 0.73 | FDPS (0.79) | FDPSGGPS1LMNA | |
| SCHEMBL27534493 | 0.71 | FDPS (0.46) | FDPSHRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273190-B1 | DIPHOSPHORIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-04-17 | — | — | EP | disclosed |
| US-4971958-A | CALCIUM METABOLISM | BOEHRINGER MANNHEIM GMBH (DE) | 1990-11-20 | — | — | US | disclosed |
| EP-0273190-A1 | Diphosphoric acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |