Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.65 |
| ▸ | LTA4H | P09960 | 12/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9794733 | 0.95 | FDPS (0.58) | FDPSLTA4H | |
| SCHEMBL8703776 | 0.79 | FDPS (1.00) | FDPSMEN1MITFLMNATP53 | |
| SCHEMBL8706931 | 0.78 | FDPS (0.97) | FDPSMEN1MITFLMNATP53 | |
| SCHEMBL9084725 | 0.76 | FDPS (0.71) | FDPSMEN1MITFLMNATP53 | |
| SCHEMBL9082964 | 0.74 | FDPS (0.67) | FDPSLMNAKMT2A | |
| SCHEMBL9806694 | 0.74 | FDPS (0.90) | FDPSMEN1MITFLMNATP53 | |
| SCHEMBL3431791 | 0.74 | FDPS (0.54) | FDPSLTA4HMEN1MITFLMNA | |
| SCHEMBL9806697 | 0.73 | FDPS (0.65) | FDPSLMNA | |
| SCHEMBL8706934 | 0.73 | FDPS (0.79) | FDPSMEN1MITFLMNATP53 | |
| SCHEMBL6890158 | 0.71 | FDPS (0.63) | FDPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002937-A | Diphosphonic acid alkyloxyalkylamines for bone disorders | BOEHRINGER MANNHEIM GMBH (DE) | 1991-03-26 | — | — | US | disclosed |
| EP-0350002-A1 | Diphosphonic-acid derivatives, process for their preparation and medicines containing those compounds | Roche Diagnostics GmbH (DE) | 1990-01-10 | — | — | EP | disclosed |