Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 7/20 | 0.83 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.83 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.83 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.83 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.83 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.83 |
| ▸ | MEN1 | O00255 | 4/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.83 |
| ▸ | MAPT | P10636 | 3/20 | 0.83 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.83 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.83 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.83 |
| ▸ | HTT | P42858 | 2/20 | 0.83 |
| ▸ | TP53 | P04637 | 1/20 | 0.83 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382806 | 0.95 | ADRA1A (0.91) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL9806909 | 0.95 | ADRA1A (0.87) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL9806899 | 0.95 | ADRA1A (0.82) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL9807029 | 0.94 | ADRA1A (0.83) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL9807024 | 0.94 | ADRA1A (0.83) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL9806968 | 0.93 | ADRA1A (0.78) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL9806895 | 0.93 | ADRA1A (0.78) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL9806962 | 0.93 | ADRA1A (0.78) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL9806971 | 0.93 | ADRA1A (0.78) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL9806943 | 0.92 | ADRA1A (0.75) | ADRA1AADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064839-A | Vasodilators, coronary disorders, hypotensive | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1991-11-12 | — | — | US | disclosed |