Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 4/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785204 | 0.94 | GGPS1 (0.40) | CYP3A4FDPSSMPD1LPAR3LPAR1 | |
| SCHEMBL11761617 | 0.91 | CYP3A4 (0.42) | CYP3A4FDPSSMPD1CES2LPAR3 | |
| SCHEMBL11513063 | 0.85 | FDPS (0.33) | CYP3A4FDPSSMPD1CES2LPAR3 | |
| SCHEMBL11443763 | 0.84 | CES2 (0.36) | CYP3A4FDPSCES2LPAR3LPAR1 | |
| SCHEMBL11445668 | 0.84 | CES2 (0.36) | CYP3A4FDPSCES2LPAR3LPAR1 | |
| SCHEMBL11761619 | 0.83 | LPAR3 (0.44) | FDPSSMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL11035246 | 0.83 | FDPS (0.36) | CYP3A4FDPSSMPD1CES2LPAR3 | |
| SCHEMBL8110809 | 0.82 | CES2 (0.42) | CYP3A4FDPSCES2LPAR3LPAR1 | |
| SCHEMBL11273070 | 0.76 | CES2 (0.51) | FDPSSMPD1CES2LPAR3LPAR1 | |
| SCHEMBL961898 | 0.76 | FDPS (0.36) | CYP3A4FDPSSMPD1TSHRGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073569-A | 13,14-dihydro-15-keto- | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1991-12-17 | — | — | US | disclosed |