Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 8/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935062 | 0.91 | PNP (0.70) | PNPTHRBKDM4EMEN1ALDH1A1 | |
| SCHEMBL15743133 | 0.90 | PNP (0.59) | PNPTHRBKDM4EMEN1ALDH1A1 | |
| SCHEMBL8196747 | 0.89 | PNP (0.58) | PNPTHRBKDM4EMEN1ALDH1A1 | |
| SCHEMBL21314870 | 0.87 | PNP (0.56) | PNPTHRBKDM4EMEN1ALDH1A1 | |
| SCHEMBL441796 | 0.85 | PNP (0.61) | PNPTHRBKDM4EMEN1ALDH1A1 | |
| SCHEMBL350396 | 0.85 | PNP (0.61) | PNPTHRBKDM4EMEN1ALDH1A1 | |
| SCHEMBL667795 | 0.85 | PNP (0.61) | PNPTHRBKDM4EMEN1ALDH1A1 | |
| SCHEMBL9960811 | 0.84 | PNP (0.71) | PNPTHRBKDM4EMEN1ALDH1A1 | |
| SCHEMBL6272728 | 0.82 | PNP (0.58) | PNPTHRBKDM4EMEN1ALDH1A1 | |
| SCHEMBL6266584 | 0.81 | PNP (0.56) | PNPTHRBKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | claimed |
| EP-0129285-B1 | PENETRATING TOPICAL PHARMACEUTICAL COMPOSITIONS CONTAINING N-(2-HYDROXYETHYL)PYRROLIDONE | THE PROCTER & GAMBLE COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
| US-4537776-A | PERCUTANEOUS DELIVERY OF ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0129284-A2 | Improved penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one | THE PROCTER & GAMBLE COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |