SCHEMBL667795

SCHEMBL667795

CCCc1nc2nc(N)[nH]c(=O)c2[nH]1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PNP P00491 6/20 0.61
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
FGFR1 P11362 1/20 0.45
FGFR2 P21802 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6272728 0.90 PNP (0.58) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL5935062 0.90 PNP (0.70) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL8522269 0.89 PNP (0.56) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL6272296 0.88 PNP (0.54) PNP
SCHEMBL7777164 0.88 PNP (0.54) PNP
SCHEMBL8536005 0.88 PNP (0.54) PNP
Hydrochloric Acid SCHEMBL258896 0.86 PNP (0.53) PNP
SCHEMBL874735 0.86 PNP (0.66) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL9806967 0.85 PNP (0.63) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL441796 0.83 PNP (0.61) PNPKDM4EMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 661 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS BRISTOL MYERS SQUIBB CO (US) 2026-05-21 US disclosed
WO-2026106956-A1 DISULFIDE-STABILIZED NOROVIRUS VIRUS-LIKE PARTICLE DESIGN MERCK SHARP & DOHME LLC (US) 2026-05-21 WO disclosed
US-12629412-B2 Betacoronavirus mRNA vaccines MODERNATX, INC. (US) 2026-05-19 US disclosed
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF ADVANCED RNA VACCINE ARV TECH INC (US) 2026-05-14 US disclosed
US-12622960-B2 Varicella zoster virus (VZV) vaccine MODERNATX, INC. (US) 2026-05-12 US disclosed
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES MODERNATX, INC. (US) 2026-04-23 US disclosed
EP-4727955-A1 CYSTEINE-SUBSTITUTED RSV-F PROTEINS GlaxoSmithKline Biologicals S.A. (BE) 2026-04-22 EP disclosed
EP-3458081-B1 POLYNUCLEOTIDES ENCODING CITRIN FOR THE TREATMENT OF CITRULLINEMIA TYPE 2 MODERNATX INC (US) 2026-04-15 EP disclosed
US-20260097110-A1 BETACORONAVIRUS mRNA VACCINES MODERNATX, INC. (US) 2026-04-09 US disclosed
US-20260091104-A1 NUCLEIC ACID VACCINES MODERNATX, INC. (US) 2026-04-02 US disclosed
EP-2451823-A2 COMPOSITIONS AND METHODS FOR ENHANCING PRODUCTION OF A BIOLOGICAL PRODUCT Alnylam Pharmaceuticals, Inc. (US) 2012-05-16 EP disclosed
EP-2451940-A1 BIOPROCESSING Alnylam Pharmaceuticals, Inc. (US) 2012-05-16 EP disclosed
EP-2451476-A1 CELL-BASED BIOPROCESSING Alnylam Pharmaceuticals, Inc. (US) 2012-05-16 EP disclosed
US-20120046346-A1 SUSTAINED POLYPEPTIDE EXPRESSION FROM SYNTHETIC, MODIFIED RNAS AND USES THEREOF IMMUNE DISEASE INSTITUTE, INC. (US) 2012-02-23 US disclosed
WO-2009155504-A9 METHODS FOR THE MODULATION OF ANGIOGENESIS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2010-04-08 WO disclosed
WO-2009155504-A2 METHODS FOR THE MODULATION OF ANGIOGENESIS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-12-23 WO disclosed
WO-2009149239-A1 METHODS OF MODULATING ANGIOGENESIS VIA TRPV4 CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-12-10 WO disclosed
EP-1017394-B1 CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES CANCER REC TECH LTD (GB) 2005-12-07 EP disclosed
US-6303618-B1 ADMINISTERING PURINE COMPOUND WHICH INHIBITS CYCLIC DEPENDENT KINASE ACTIVITY FOR THERAPY OF TUMOR OR OTHER CELL PROLIFERATION DISORDER CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 2001-10-16 US disclosed
WO-1999002162-A9 CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES CANCER RES CAMPAIGN TECH (GB) 1999-07-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097110-A1 BETACORONAVIRUS mRNA VACCINES RNMT, RNGTT, METTL16 PNP 37/4885KDM4E 1943/4885MEN1 2458/4885
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS RNGTT, CDA, DCTD PNP 14/4885KDM4E 3277/4885MEN1 4354/4885
US-12629412-B2 Betacoronavirus mRNA vaccines RNMT, RNGTT, METTL16 PNP 36/4885KDM4E 1991/4885MEN1 2103/4885
US-20260091104-A1 NUCLEIC ACID VACCINES RNMT, NSUN2, AMPD1 PNP 14/4885KDM4E 1239/4885MEN1 1835/4885
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES RNMT, METTL16, NSUN2 PNP 317/4885KDM4E 2008/4885MEN1 2371/4885
US-12622960-B2 Varicella zoster virus (VZV) vaccine NSUN2, RNMT, RNGTT PNP 361/4885KDM4E 260/4885MEN1 3114/4885
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF UPF1, NSUN2, CD4 PNP 460/4885KDM4E 1144/4885MEN1 2586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.