SCHEMBL350396

SCHEMBL350396

Nc1nc2nc(CCO)[nH]c2c(=O)[nH]1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PNP P00491 8/20 0.61
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
FGFR1 P11362 1/20 0.45
FGFR2 P21802 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5935062 0.90 PNP (0.70) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL14079841 0.86 PNP (0.66) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL2346356 0.85 PNP (0.51) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL9806967 0.85 PNP (0.63) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL667795 0.83 PNP (0.61) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL441796 0.83 PNP (0.61) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL7617798 0.83 PNP (0.53) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL8361197 0.83 PNP (0.53) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL7442898 0.83 PNP (0.53) PNPKDM4EMEN1ALDH1A1MAPT
SCHEMBL9960811 0.82 PNP (0.71) PNPKDM4EMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250305030-A1 DNA ADDUCTOMICS BY MASS TAG PRELABELING UNIV NORTHEASTERN (US) 2025-10-02 US disclosed
US-12359243-B2 DNA adductomics by mass tag prelabeling NORTHEASTERN UNIVERSITY (US) 2025-07-15 US disclosed
US-20210340603-A1 DNA ADDUCTOMICS BY MASS TAG PRELABELING NORTHEASTERN UNIVERSITY 2021-11-04 US disclosed
CN-101680029-B Nucleic acid detection OXITEC LTD 2013-09-25 CN disclosed
US-20120015874-A1 NOVEL INHIBITORS OF RETROVIRAL REVERSE TRANSCRIPTACE THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2012-01-19 US disclosed
US-8030475-B2 Inhibitors of retroviral reverse transcriptase THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2011-10-04 US disclosed
CN-101680029-A Nucleic acid detection OXITEC LTD 2010-03-24 CN disclosed
US-20090305281-A1 NOVEL INHIBITORS OF RETROVIRAL REVERSE TRANSCRIPTACE THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2009-12-10 US disclosed
US-20040161361-A1 Apparatus and method for sterilization of medical equipments, pharmaceutical products and biologically contaminated articles UHM, HAN S. 2004-08-19 US disclosed