Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154744 | 0.83 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL3109968 | 0.79 | ATAD2 (0.42) | ATAD2BRD4ALDH1A1HTTGFER | |
| SCHEMBL10767939 | 0.77 | CHRM2 (0.61) | CHRM2CHRM4CHRM1CHRM3POLB | |
| SCHEMBL13181035 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HTTL3MBTL1PDK1PDK2 | |
| SCHEMBL2267570 | 0.70 | HTR2A (0.45) | ATAD2BRD4ALDH1A1GFERGAA | |
| SCHEMBL12351772 | 0.70 | PTPN11 (0.38) | CHRM2CHRM4CHRM1CHRM3POLB | |
| SCHEMBL28152073 | 0.70 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL13271341 | 0.70 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6844552 | 0.69 | HTR2A (0.44) | ATAD2BRD4ALDH1A1GFERGAA | |
| SCHEMBL10943068 | 0.69 | MEN1 (0.37) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071968-A | Lightfastness, compatibility with other dyes | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0388353-A1 | Azodyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-09-19 | — | — | EP | disclosed |