⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483605 | 0.74 | — | — | |
| SCHEMBL3792842 | 0.69 | — | — | |
| SCHEMBL2209081 | 0.69 | LMNA (0.38) | — | |
| SCHEMBL12237923 | 0.67 | — | — | |
| SCHEMBL21638818 | 0.66 | ALDH1A1 (0.31) | — | |
| SCHEMBL28814076 | 0.61 | — | — | |
| SCHEMBL21822089 | 0.60 | LMNA (0.44) | — | |
| SCHEMBL22325620 | 0.60 | LMNA (0.44) | — | |
| SCHEMBL720248 | 0.59 | — | — | |
| SCHEMBL27704143 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | claimed |
| EP-0129285-B1 | PENETRATING TOPICAL PHARMACEUTICAL COMPOSITIONS CONTAINING N-(2-HYDROXYETHYL)PYRROLIDONE | THE PROCTER & GAMBLE COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
| US-4537776-A | PERCUTANEOUS DELIVERY OF ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0129285-A2 | Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl)pyrrolidone | THE PROCTER & GAMBLE COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |
| EP-0129284-A2 | Improved penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one | THE PROCTER & GAMBLE COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |