Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971722 | 0.76 | HPGD (0.36) | HPGDHSD17B10MEN1KMT2APGK1 | |
| SCHEMBL8625037 | 0.75 | HPGD (0.41) | HPGDHSD17B10CYP3A4USP2MEN1 | |
| SCHEMBL30411660 | 0.75 | HPGD (0.38) | HPGDHSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL6966666 | 0.75 | HPGD (0.38) | HPGDHSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL30631691 | 0.75 | HPGD (0.40) | HPGDHSD17B10CYP3A4USP2MEN1 | |
| SCHEMBL18077441 | 0.73 | HPGD (0.39) | HPGDHSD17B10CYP3A4USP2MEN1 | |
| SCHEMBL8573718 | 0.73 | ALDH1A1 (0.38) | HPGDHSD17B10MEN1KMT2APOLB | |
| SCHEMBL10701771 | 0.71 | CYP3A4 (0.41) | HPGDCYP3A4USP2MEN1KMT2A | |
| SCHEMBL22599825 | 0.70 | HSD17B10 (0.37) | HPGDHSD17B10CYP3A4USP2MEN1 | |
| SCHEMBL6962732 | 0.70 | ALDH1A1 (0.36) | HPGDHSD17B10MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211605-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-05-15 | — | — | EP | disclosed |
| US-4795487-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1989-01-03 | — | — | US | disclosed |
| EP-0211605-A2 | Herbicidal Cyclohexane-1,3-dione Derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-02-25 | — | — | EP | disclosed |