Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.57 |
| ▸ | NPY1R | P25929 | 8/20 | 0.57 |
| ▸ | NPY2R | P49146 | 6/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 4/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30331385 | 0.95 | NPY4R (0.61) | NPY4RNPY1RNPY2RNPY5ROPRD1 | |
| SCHEMBL31233596 | 0.92 | NPY4R (0.60) | NPY4RNPY1RNPY2RNPY5RBACE1 | |
| SCHEMBL30331324 | 0.91 | NPY4R (0.57) | NPY4RNPY1RNPY2RNPY5ROPRD1 | |
| SCHEMBL29649727 | 0.90 | NPY4R (0.65) | NPY4RNPY1RNPY2RNPY5ROPRD1 | |
| SCHEMBL29649769 | 0.90 | NPY4R (0.65) | NPY4RNPY1RNPY2RNPY5ROPRD1 | |
| Thymopentin SCHEMBL989519 | 0.90 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5ROPRD1 | |
| Thymopentin SCHEMBL7498758 | 0.90 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5ROPRD1 | |
| SCHEMBL30331711 | 0.90 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5ROPRD1 | |
| Thymopentin SCHEMBL44001 | 0.90 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5ROPRD1 | |
| Thymopentin SCHEMBL29512423 | 0.90 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5ROPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146266-B1 | ENZYME-RESISTANT IMMUNOMODULATORY PEPTIDES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0146266-A2 | Enzyme-resistant immunomodulatory peptides | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-06-26 | — | — | EP | disclosed |
| US-4505853-A | GLANDULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-03-19 | — | — | US | disclosed |