Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3000480 | 0.77 | — | — | |
| SCHEMBL16429781 | 0.77 | — | — | |
| SCHEMBL523257 | 0.77 | — | — | |
| SCHEMBL9950602 | 0.76 | CRBN (0.48) | BRD4CRBNTP53KMT2ANPSR1 | |
| SCHEMBL1536267 | 0.74 | MAP3K14 (0.43) | BRD4CRBNKMT2ALMNACYP2C19 | |
| SCHEMBL7837579 | 0.74 | BRD4 (0.39) | BRD4MMP3MMP8TYMP | |
| SCHEMBL11821261 | 0.73 | BRD4 (0.45) | BRD4TYMPMAPT | |
| SCHEMBL21524286 | 0.73 | ALDH1A1 (0.46) | CRBNTP53KMT2ASMN1; SMN2NR2F2 | |
| SCHEMBL24111511 | 0.70 | CRBN (0.46) | CRBNTP53KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL19438354 | 0.70 | CRBN (0.52) | BRD4CRBNTP53KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125683-A1 | TREATMENT OF CANCERS HAVING A DRUG-RESISTANT MESENCHYMAL CELL STATE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4709874-A1 | MODULATORS OF PROTEIN SECRETION | Sanofi (FR) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024231896-A1 | MODULATORS OF PROTEIN SECRETION | SANOFI (FR) | 2024-11-14 | — | — | WO | disclosed |
| WO-2024192141-A1 | TREATMENT OF CANCERS HAVING A DRUG-RESISTANT MESENCHYMAL CELL STATE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-09-19 | — | — | WO | disclosed |
| US-5037836-A | Antifungal and antitumor agent | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0432697-A2 | BU-4146T antibiotic | Bristol-Myers Squibb Company (US) | 1991-06-19 | — | — | EP | disclosed |
| US-5002959-A | Antitumor agents, fungicides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125683-A1 | TREATMENT OF CANCERS HAVING A DRUG-RESISTANT MESENCHYMAL CELL STATE | ACTR2, RPS6KB2, EPB41L2 | BRD4 1313/4885CRBN 642/4885TP53 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.