Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 15/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | KDR | P35968 | 17/20 | 0.65 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.58 |
| ▸ | KIT | P10721 | 10/20 | 0.58 |
| ▸ | CSF1R | P07333 | 2/20 | 0.58 |
| ▸ | FLT4 | P35916 | 2/20 | 0.58 |
| ▸ | CIT | O14578 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | HLA-A | P04439 | 1/20 | 0.58 |
| ▸ | RET | P07949 | 1/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.58 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.58 |
| ▸ | FRK | P42685 | 1/20 | 0.58 |
| ▸ | CDK8 | P49336 | 1/20 | 0.58 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.58 |
| ▸ | STK3 | Q13188 | 1/20 | 0.58 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.58 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204447 | 0.87 | FLT1 (1.00) | FLT1MEN1KMT2AKDRPDGFRB | |
| SCHEMBL905680 | 0.87 | KDR (0.76) | FLT1KDRPDGFRBKITCSF1R | |
| SCHEMBL6608078 | 0.78 | FLT1 (0.80) | FLT1MEN1KMT2AKDRPDGFRB | |
| SCHEMBL5753555 | 0.77 | FLT1 (0.80) | FLT1MEN1KMT2AKDRPDGFRB | |
| SCHEMBL5754939 | 0.76 | KDR (0.65) | FLT1MEN1KMT2AKDRPDGFRB | |
| SCHEMBL1651296 | 0.76 | FLT1 (0.79) | FLT1MEN1KMT2AKDRPDGFRB | |
| SCHEMBL14267794 | 0.76 | FLT1 (0.65) | FLT1MEN1KMT2AKDRPDGFRB | |
| SCHEMBL14267795 | 0.75 | FLT1 (0.63) | FLT1MEN1KMT2AKDRPDGFRB | |
| SCHEMBL5332250 | 0.75 | FLT1 (0.62) | FLT1MEN1KMT2AKDRPDGFRB | |
| SCHEMBL5753111 | 0.74 | KMT2A (0.52) | FLT1MEN1KMT2AKDRPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3106875-A | — | — | None | — | — | JP | disclosed |
| JP-H03106875-A | 1-(3-PYRIDYLMETHYL)PHTHALAZINE DERIVATIVE | MORISHITA PHARMACEUT CO LTD | 1991-05-07 | — | — | JP | disclosed |