Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195412 | 1.00 | LMNA (0.48) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL5191874 | 1.00 | LMNA (0.48) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8327144 | 1.00 | LMNA (0.48) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL27676851 | 1.00 | LMNA (0.48) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| Bromide SCHEMBL27824093 | 0.98 | LMNA (0.46) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL758600 | 0.91 | ALDH1A1 (0.56) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL2332275 | 0.91 | LMNA (0.52) | LMNATSHRDNM1PLA2G1BPLA2G2A | |
| SCHEMBL10347493 | 0.91 | LMNA (0.52) | LMNATSHRDNM1PLA2G1BPLA2G2A | |
| SCHEMBL28674976 | 0.91 | LMNA (0.52) | LMNATSHRDNM1PLA2G1BPLA2G2A | |
| SCHEMBL10666915 | 0.91 | LMNA (0.52) | LMNATSHRDNM1PLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323163-B1 | SHIFT-FEEL DURABILITY ENHANCEMENT | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-05-29 | — | — | EP | disclosed |
| EP-0323163-A1 | Shift-feel Durability enhancement | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1989-07-05 | — | — | EP | disclosed |
| US-4795583-A | FRICTION MODIFIER FOR AUTOMATIC TRANSMISSION FLUIDS CONTAINING AN ALIPHATIC TERTIARY AMINE, ALIPHATIC DIAMINE AND-OR N-SUBSTITUTED DIALKANOLAMINE | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1989-01-03 | — | — | US | disclosed |