SCHEMBL9807741

SCHEMBL9807741

C=CN(C=C)CCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 5/20 0.48
TSHR P16473 5/20 0.46
THRB P10828 1/20 0.42
ZDHHC20 Q5W0Z9 2/20 0.39
ZDHHC2 Q9UIJ5 2/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 2/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
FAAH O00519 1/20 0.36
GBA1 P04062 1/20 0.35
MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7544078 1.00 DNM1 (0.48) DNM1TSHRTHRBZDHHC20ZDHHC2
SCHEMBL10071590 1.00 DNM1 (0.48) DNM1TSHRTHRBZDHHC20ZDHHC2
SCHEMBL10071594 1.00 DNM1 (0.48) DNM1TSHRTHRBZDHHC20ZDHHC2
Hydrochloric Acid SCHEMBL27924643 0.97 DNM1 (0.50) DNM1TSHRTHRBZDHHC20ZDHHC2
SCHEMBL10071593 0.97 DNM1 (0.43) DNM1TSHRTHRBZDHHC20ZDHHC2
SCHEMBL10071596 0.89
SCHEMBL10570733 0.86
Hydrochloric Acid SCHEMBL10600098 0.86 TSHR (0.39) DNM1TSHRTHRBCA12CA1
SCHEMBL8087564 0.86 ADH1C (0.46) DNM1TSHRTHRBZDHHC20ZDHHC2
SCHEMBL8086267 0.86 ADH1C (0.46) DNM1TSHRTHRBZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0323163-B1 SHIFT-FEEL DURABILITY ENHANCEMENT ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-05-29 EP disclosed
EP-0323163-A1 Shift-feel Durability enhancement ETHYL PETROLEUM ADDITIVES, INC. (US) 1989-07-05 EP disclosed
US-4795583-A FRICTION MODIFIER FOR AUTOMATIC TRANSMISSION FLUIDS CONTAINING AN ALIPHATIC TERTIARY AMINE, ALIPHATIC DIAMINE AND-OR N-SUBSTITUTED DIALKANOLAMINE ETHYL PETROLEUM ADDITIVES, INC. (US) 1989-01-03 US disclosed