SCHEMBL9807748

SCHEMBL9807748

Cc1cc(C2(c3cc(C)c(O)c(C(C)(C)C)c3)CCCCC2)cc(C(C)(C)C)c1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.71
ESR1 P03372 4/20 0.51
ESR2 Q92731 4/20 0.51
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
CA2 P00918 2/20 0.41
POLB P06746 1/20 0.41
TYR P14679 1/20 0.41
LMNA P02545 2/20 0.38
ALOX12 P18054 2/20 0.38
CA1 P00915 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
KDM4E B2RXH2 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALOX15 P16050 2/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17532649 0.98 ACHE (0.68) ACHEESR1ESR2CYP1A2CYP2C9
SCHEMBL297823 0.90 ACHE (0.58) ACHEESR1ESR2CYP1A2CYP2C9
SCHEMBL17532650 0.84 CA2 (0.50) ACHEESR1ESR2CYP1A2CYP2C9
SCHEMBL673355 0.84 ACHE (1.00) ACHEESR1ESR2CYP2C9ALDH1A1
SCHEMBL672596 0.84 ACHE (1.00) ACHEESR1ESR2CYP2C9ALDH1A1
SCHEMBL674887 0.84 ACHE (1.00) ACHEESR1ESR2CYP2C9ALDH1A1
SCHEMBL10941758 0.84 ACHE (1.00) ACHEESR1ESR2CYP2C9ALDH1A1
SCHEMBL675004 0.84 ACHE (1.00) ACHEESR1ESR2CYP2C9ALDH1A1
SCHEMBL673424 0.84 ACHE (1.00) ACHEESR1ESR2CYP2C9ALDH1A1
SCHEMBL673351 0.84 ACHE (1.00) ACHEESR1ESR2CYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5019548-A Basic Dye, Color Acceptor, Benzyloxyphenyl Methyl Sulfide KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-05-28 US disclosed
US-4985393-A Bis/hydroxyphenylthio/ Compounds KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-01-15 US disclosed
EP-0373561-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-06-20 EP disclosed
US-4013618-A NITROGEN-CONTAINING STABILIZER TOYOBO CO., LTD. (JA) 1977-03-22 US disclosed
US-3957905-A HALOGENATED BISPHENYL COMPOUND, ANTIMONY COMPOUND TOYO BOSEKI KABUSHIKI KAISHA (JA) 1976-05-18 US disclosed