Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166352 | 0.76 | TSHR (0.36) | ALDH1A1TSHRPTPN7HMGCREPHX2 | |
| SCHEMBL5166359 | 0.76 | TSHR (0.36) | ALDH1A1TSHRPTPN7HMGCREPHX2 | |
| SCHEMBL5606954 | 0.76 | EPHX2 (0.41) | MEN1KMT2AALDH1A1TSHREPHX1 | |
| SCHEMBL28375291 | 0.74 | RELA (0.50) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3626574 | 0.73 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3622908 | 0.73 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3620310 | 0.73 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL21467785 | 0.73 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3626654 | 0.73 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3619312 | 0.73 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323163-B1 | SHIFT-FEEL DURABILITY ENHANCEMENT | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-05-29 | — | — | EP | disclosed |
| EP-0323163-A1 | Shift-feel Durability enhancement | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1989-07-05 | — | — | EP | disclosed |
| US-4795583-A | FRICTION MODIFIER FOR AUTOMATIC TRANSMISSION FLUIDS CONTAINING AN ALIPHATIC TERTIARY AMINE, ALIPHATIC DIAMINE AND-OR N-SUBSTITUTED DIALKANOLAMINE | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1989-01-03 | — | — | US | disclosed |