Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4315142 | 0.98 | MEN1 (0.59) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL7298429 | 0.94 | MEN1 (0.59) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL6129417 | 0.92 | MEN1 (0.61) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL572406 | 0.92 | MEN1 (0.61) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL1972096 | 0.92 | MEN1 (0.61) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL6255301 | 0.92 | MEN1 (0.61) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL7775575 | 0.92 | MEN1 (0.61) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL12970034 | 0.92 | MEN1 (0.55) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL9549560 | 0.89 | THRB (0.54) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL9549581 | 0.89 | THRB (0.54) | MEN1KMT2AHTTTHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323163-B1 | SHIFT-FEEL DURABILITY ENHANCEMENT | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-05-29 | — | — | EP | disclosed |
| EP-0323163-A1 | Shift-feel Durability enhancement | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1989-07-05 | — | — | EP | disclosed |
| US-4795583-A | FRICTION MODIFIER FOR AUTOMATIC TRANSMISSION FLUIDS CONTAINING AN ALIPHATIC TERTIARY AMINE, ALIPHATIC DIAMINE AND-OR N-SUBSTITUTED DIALKANOLAMINE | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1989-01-03 | — | — | US | disclosed |