Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549560 | 1.00 | THRB (0.54) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL9818091 | 0.98 | THRB (0.52) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL9549114 | 0.95 | HTT (0.54) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL23606367 | 0.93 | THRB (0.46) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL19637028 | 0.91 | MEN1 (0.50) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL28138868 | 0.91 | MEN1 (0.50) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL9807805 | 0.91 | MEN1 (0.50) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL5162321 | 0.91 | MEN1 (0.50) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL115377 | 0.91 | MEN1 (0.50) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL12120261 | 0.90 | HTT (0.54) | THRBHTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288515-B1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | ISP INVESTMENTS INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| EP-0288515-A4 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | — | 1990-09-26 | — | — | EP | disclosed |
| US-4830850-A | CONDITIONERS, SOFTENERS, PRESERVATIVES | GAF CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| EP-0288515-A1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS. | GAF CORP (US) | 1988-11-02 | — | — | EP | disclosed |
| WO-1988002985-A1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | GAF CORPORATION (US) | 1988-05-05 | — | — | WO | disclosed |