Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807868 | 0.83 | GSK3B (0.38) | RAB9ASMN1; SMN2HCRTR1TP53MAPT | |
| SCHEMBL9807905 | 0.78 | SMN1; SMN2 (0.35) | RAB9ASMN1; SMN2HCRTR1TP53MAPT | |
| SCHEMBL9807926 | 0.69 | GSK3B (0.41) | MAPTMAPK1NPC1KMT2AKDM4E | |
| SCHEMBL9807923 | 0.69 | MAPT (0.41) | RAB9ASMN1; SMN2HCRTR1TP53MAPT | |
| SCHEMBL9808007 | 0.69 | MAPT (0.41) | RAB9ASMN1; SMN2CYP1A2HCRTR1TP53 | |
| SCHEMBL11757772 | 0.68 | HTR1B (0.49) | HTR1BDRD3RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL12145408 | 0.68 | ALDH1A1 (0.43) | RAB9ASMN1; SMN2CYP1A2HCRTR1TP53 | |
| SCHEMBL11419712 | 0.62 | JAK2 (0.45) | RAB9ASMN1; SMN2MAPK1NPC1KMT2A | |
| SCHEMBL10309392 | 0.61 | PDE10A (0.55) | — | |
| SCHEMBL11408772 | 0.60 | PDE10A (0.40) | RAB9ASMN1; SMN2HCRTR1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994448-A | Analgesics, anesthetics, muscle relaxants | EGIS GYOGYSZERGYAR (HU) | 1991-02-19 | — | — | US | disclosed |