Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 5/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807868 | 0.82 | GSK3B (0.38) | SMN1; SMN2MAPTHCRTR1TP53ALOX15 | |
| SCHEMBL9808019 | 0.78 | HTR1B (0.36) | SMN1; SMN2MAPTHCRTR1TP53ALOX15 | |
| SCHEMBL9807923 | 0.72 | MAPT (0.41) | SMN1; SMN2MAPTHCRTR1TP53ALOX15 | |
| SCHEMBL9808007 | 0.72 | MAPT (0.41) | SMN1; SMN2MAPTHCRTR1TP53ALOX15 | |
| SCHEMBL12145408 | 0.71 | ALDH1A1 (0.43) | SMN1; SMN2MAPTHCRTR1TP53ALOX15 | |
| SCHEMBL9807926 | 0.68 | GSK3B (0.41) | MAPTMAPK1L3MBTL1LMNAHTT | |
| SCHEMBL11416817 | 0.65 | DHODH (0.50) | SMN1; SMN2MAPTTP53MAPK1RAB9A | |
| SCHEMBL11408756 | 0.64 | IDO1 (0.41) | SMN1; SMN2MAPTHCRTR1TP53ALOX15 | |
| SCHEMBL10309392 | 0.64 | PDE10A (0.55) | PDE10A | |
| SCHEMBL11262382 | 0.63 | DHODH (0.55) | SMN1; SMN2MAPTRAB9APDE10ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994448-A | Analgesics, anesthetics, muscle relaxants | EGIS GYOGYSZERGYAR (HU) | 1991-02-19 | — | — | US | disclosed |