Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 11/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 10/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 8/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.98 |
| ▸ | BLM | P54132 | 1/20 | 0.98 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | PKM | P14618 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14883668 | 1.00 | OPRD1 (1.00) | OPRD1OPRM1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL18475510 | 1.00 | OPRD1 (1.00) | OPRD1OPRM1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL29796720 | 1.00 | OPRD1 (1.00) | OPRD1OPRM1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL12657346 | 1.00 | OPRD1 (1.00) | OPRD1OPRM1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL13172000 | 1.00 | OPRD1 (1.00) | OPRD1OPRM1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL12137748 | 1.00 | OPRD1 (1.00) | OPRD1OPRM1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL15241475 | 1.00 | OPRD1 (1.00) | OPRD1OPRM1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL15803772 | 1.00 | OPRD1 (1.00) | OPRD1OPRM1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL20306870 | 1.00 | OPRD1 (1.00) | OPRD1OPRM1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL46197 | 1.00 | OPRD1 (1.00) | OPRD1OPRM1OPRK1CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071985-A | Demethylation with sulfonic acid derivative in the presence of a sulfide | SANOFI (FR) | 1991-12-10 | — | — | US | disclosed |