Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679951 | 0.95 | CYP2D6 (0.61) | ALDH1A1CYP2D6CYP2C19DRD2DRD4 | |
| SCHEMBL1592876 | 0.92 | TDP1 (0.60) | ALDH1A1CYP2D6CYP2C19DRD2DRD4 | |
| SCHEMBL7496819 | 0.91 | ALDH1A1 (0.56) | ALDH1A1CYP2D6CYP2C19DRD2DRD4 | |
| SCHEMBL13313250 | 0.91 | ALDH1A1 (0.56) | ALDH1A1CYP2D6CYP2C19DRD2DRD4 | |
| SCHEMBL6304558 | 0.91 | ALDH1A1 (0.56) | ALDH1A1CYP2D6CYP2C19DRD2DRD4 | |
| SCHEMBL20530525 | 0.89 | ALDH1A1 (0.58) | ALDH1A1CYP2D6CYP2C19DRD2DRD4 | |
| SCHEMBL20530589 | 0.89 | ALDH1A1 (0.58) | ALDH1A1CYP2D6CYP2C19DRD2DRD4 | |
| SCHEMBL22207345 | 0.89 | ALDH1A1 (0.58) | ALDH1A1CYP2D6CYP2C19DRD2DRD4 | |
| SCHEMBL22207487 | 0.89 | ALDH1A1 (0.58) | ALDH1A1CYP2D6CYP2C19DRD2DRD4 | |
| SCHEMBL22207292 | 0.89 | ALDH1A1 (0.58) | ALDH1A1CYP2D6CYP2C19DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168161-B2 | Biaryl phenoxy group IV transition metal catalysts for olefin polymerization | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-11-09 | — | — | US | disclosed |
| WO-2020185494-A1 | BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION WITH CHAIN TRANSFER CAPABILITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-09-17 | — | — | WO | disclosed |
| WO-2020131566-A1 | BIARYL PHENOXY GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-06-25 | — | — | WO | disclosed |
| US-20200157254-A1 | BIARYL PHENOXY GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYERMIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-05-21 | — | — | US | disclosed |
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168161-B2 | Biaryl phenoxy group IV transition metal catalysts for olefin polymerization | PPOX, LIG4, PARG | ALDH1A1 1613/4885CYP2D6 652/4885CYP2C19 998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.