Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.53 |
| ▸ | YAP1 | P46937 | 1/20 | 0.53 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.53 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808027 | 0.89 | CNR2 (0.49) | TEAD1YAP1TEAD4TEAD2MTNR1A | |
| SCHEMBL9808094 | 0.89 | TEAD1 (0.53) | TEAD1YAP1TEAD4TEAD2MTNR1A | |
| SCHEMBL9808073 | 0.87 | TEAD1 (0.60) | TEAD1YAP1TEAD4TEAD2MTNR1A | |
| SCHEMBL21963810 | 0.87 | MTNR1A (0.54) | TEAD1YAP1TEAD4TEAD2MTNR1A | |
| SCHEMBL8388519 | 0.86 | EPHX1 (0.54) | MTNR1AMTNR1BALDH1A1HPGDHTT | |
| SCHEMBL8388750 | 0.86 | EPHX1 (0.54) | MTNR1AMTNR1BALDH1A1HPGDHTT | |
| SCHEMBL9808086 | 0.85 | TEAD1 (0.58) | TEAD1YAP1TEAD4TEAD2MTNR1A | |
| SCHEMBL8412413 | 0.85 | MTNR1A (0.72) | TEAD1YAP1TEAD4TEAD2MTNR1A | |
| SCHEMBL9808122 | 0.84 | HPGD (0.57) | TEAD1YAP1TEAD4TEAD2MTNR1A | |
| SCHEMBL9808246 | 0.84 | ALDH1A1 (0.66) | TEAD1YAP1TEAD4TEAD2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |