⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96803 | 0.88 | — | — | |
| SCHEMBL3020365 | 0.88 | — | — | |
| SCHEMBL1895073 | 0.87 | ALDH1A1 (0.38) | — | |
| SCHEMBL911290 | 0.87 | EPHX2 (0.30) | — | |
| SCHEMBL1894593 | 0.87 | ALDH1A1 (0.43) | — | |
| SCHEMBL2913315 | 0.87 | ALDH1A1 (0.43) | — | |
| SCHEMBL1897478 | 0.87 | ALDH1A1 (0.32) | — | |
| SCHEMBL4165259 | 0.87 | — | — | |
| SCHEMBL887220 | 0.87 | — | — | |
| SCHEMBL21114254 | 0.86 | ADH1B (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 382 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019935-B | Water-based lignin-based epoxy resin coating and preparation method thereof | 广东拓普合成科技股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119019935-A | Water-based lignin-based epoxy resin coating and preparation method thereof | 广东拓普合成科技股份有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-109438203-A | A kind of preparation method of 2- cyclopropylpropanal | 淮安国瑞化工有限公司 | 2019-03-08 | — | — | CN | claimed |
| EP-2976339-B1 | GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-06-27 | — | — | EP | claimed |
| US-9957264-B2 | Geminally substituted cyanoethylpyrazolo pyridones as Janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-05-01 | — | — | US | claimed |
| CN-105189498-B | Geminally substituted cyanoethylpyrazolopyridinones as JANUS kinase inhibitors | 默沙东公司 | 2017-06-27 | — | — | CN | claimed |
| US-20160272632-A1 | GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-09-22 | — | — | US | claimed |
| EP-2976339-A1 | GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2016-01-27 | — | — | EP | claimed |
| CN-105189498-A | Geminally substituted cyanoethylpyrazolopyridinones as JANUS kinase inhibitors | MERCK SHARP & DOHME | 2015-12-23 | — | — | CN | claimed |
| CN-105152886-A | Synthetic method of 1-(4-chlorophenyl)-2-cyclopropyl-1-propanone | RUDONG ZHONGYI CHEMICAL CO LTD | 2015-12-16 | — | — | CN | claimed |
| WO-2014146491-A1 | GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-09-25 | — | — | WO | claimed |
| US-8486892-B2 | Blood coagulation factor inhibitors | NOVO NORDISK HEALTH CARE AG (CH) | 2013-07-16 | — | — | US | claimed |
| US-8357675-B2 | 17-alpha-substituted derivatives of estradiol with wound-healing activity | EUTICALS S.P.A. (IT) | 2013-01-22 | — | — | US | claimed |
| US-20110003752-A1 | New Blood Coagulation Factor Inhibitors | NOVO NORDISK HEALTH CARE A/G (CH) | 2011-01-06 | — | — | US | claimed |
| EP-2235042-A1 | NEW BLOOD COAGULATION FACTOR INHIBITORS | Novo Nordisk Health Care AG (CH) | 2010-10-06 | — | — | EP | claimed |
| WO-2009092758-A1 | NEW BLOOD COAGULATION FACTOR INHIBITORS | NOVO NORDISK HEALTH CARE AG (DK) | 2009-07-30 | — | — | WO | claimed |
| US-4727079-A | Brain-specific dopaminergic activity involving dihydropyridine carboxamides, dihydroquinoline and isoquinoline carboxamides | UNIVERSITY OF FLORIDA (US) | 1988-02-23 | — | — | US | claimed |
| US-12528822-B2 | Cycloalkane-1,3-diamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2026-01-20 | — | — | US | disclosed |
| US-4094983-A | \"KETO\" SYMPATHOMIMETIC AMINES | INTERX RESEARCH CORPORATION (US) | 1978-06-13 | — | — | US | disclosed |
| US-4035405-A | Novel synthesis for preparing the hydrochloride salt of selected catecholamine derivatives | INTERX RESEARCH CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |