Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808316 | 1.00 | THRB (0.45) | THRBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9808318 | 1.00 | THRB (0.45) | THRBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9603122 | 0.84 | MEN1 (0.64) | THRBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9603127 | 0.84 | MEN1 (0.64) | THRBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9603119 | 0.84 | MEN1 (0.64) | THRBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9808337 | 0.81 | THRB (0.68) | THRBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4575883 | 0.81 | THRB (0.68) | THRBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9808268 | 0.81 | THRB (0.68) | THRBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9602233 | 0.81 | ARG1 (0.43) | THRBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6194188 | 0.79 | GRIN2D (0.41) | THRBGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203891-B1 | CERTAIN PHOSPHONIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-05-15 | — | — | EP | disclosed |
| EP-0203891-A2 | Certain phosphonic acids and derivatives | CIBA-GEIGY AG (CH) | 1986-12-03 | — | — | EP | disclosed |