Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808253 | 0.92 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9AENPP2HTT | |
| SCHEMBL7399283 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AHTTHTR2C | |
| SCHEMBL31367138 | 0.77 | ELANE (0.48) | SMN1; SMN2NPC1RAB9AHTTHTR2C | |
| SCHEMBL20146330 | 0.77 | HTR2C (0.48) | SMN1; SMN2NPC1RAB9AHTTHTR2C | |
| SCHEMBL3710479 | 0.72 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AHTTHTR2C | |
| SCHEMBL31105176 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL29053828 | 0.71 | NPC1 (0.46) | SMN1; SMN2NPC1RAB9AHTTHTR2C | |
| SCHEMBL31367121 | 0.71 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9AHTTHTR2C | |
| SCHEMBL9808275 | 0.70 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9AENPP2HTT | |
| SCHEMBL205549 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203891-B1 | CERTAIN PHOSPHONIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-05-15 | — | — | EP | disclosed |