Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367105 | 0.91 | GNAI3 (0.32) | GNAI3GNAO1GNAI1 | |
| SCHEMBL28545323 | 0.86 | CYP1A2 (0.33) | GNAI3GNAO1GNAI1 | |
| Bromide SCHEMBL28392876 | 0.84 | CYP1A2 (0.32) | GNAI3GNAO1GNAI1 | |
| Bromide SCHEMBL28388954 | 0.79 | CYP1A2 (0.33) | — | |
| SCHEMBL23650094 | 0.78 | DNM1 (0.38) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL29061567 | 0.72 | GNAI3 (0.31) | GNAI3GNAO1GNAI1 | |
| SCHEMBL11097797 | 0.71 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9762479 | 0.70 | TDP1 (0.40) | ALDH1A1EPHX1 | |
| SCHEMBL2426157 | 0.70 | TDP1 (0.40) | ALDH1A1EPHX1 | |
| SCHEMBL5339882 | 0.70 | TDP1 (0.40) | ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425584-A1 | PROSTAGLANDIN-DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY | IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) | 1991-05-08 | — | — | EP | disclosed |
| WO-1990003170-A2 | PROSTAGLANDIN-DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY | IBI ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.P.A. (IT) | 1990-04-05 | — | — | WO | disclosed |