Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412642 | 0.78 | KMT2A (0.42) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1014580 | 0.72 | KDM4E (0.58) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL798009 | 0.72 | MEN1 (0.50) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10406368 | 0.71 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL16447196 | 0.71 | TSHR (0.44) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL19744027 | 0.70 | TSHR (0.47) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL7997265 | 0.70 | KDM4E (0.55) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2902593 | 0.70 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL18585976 | 0.70 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL17146906 | 0.69 | TSHR (0.59) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956369-A | HYPOTENSIVE AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1990-09-11 | — | — | US | claimed |
| US-5021436-A | Antiulcer, anticoagulant, antiischaemic agent | BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) | 1991-06-04 | — | — | US | disclosed |
| US-4999362-A | Hypotensive, Antiulcer, Cytoprotective, Antithrombotic Agents | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1991-03-12 | — | — | US | disclosed |