Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2438523 | 0.85 | TSHR (0.46) | TSHRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8627470 | 0.83 | ALDH1A1 (0.50) | TSHRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2441803 | 0.82 | TSHR (0.40) | TSHRALDH1A1KMT2AKDM4ERAB9A | |
| SCHEMBL2440375 | 0.81 | ALDH1A1 (0.51) | TSHRALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL16446598 | 0.80 | KDM4E (0.57) | TSHRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11804105 | 0.76 | SMN1; SMN2 (0.43) | ALDH1A1KMT2AKDM4ERAB9ACYP1A2 | |
| SCHEMBL15415001 | 0.75 | LMNA (0.44) | TSHRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15415100 | 0.75 | KMT2A (0.56) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL3453344 | 0.74 | CYP2C9 (0.51) | TSHRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15415637 | 0.72 | JAK2 (0.53) | TSHRALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311830-B | Microbicidal oxadiazole derivatives | 先正达参股股份有限公司 | 2023-02-24 | — | — | CN | disclosed |
| US-11026427-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-06-08 | — | — | US | disclosed |
| US-20190223441-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-07-25 | — | — | US | disclosed |
| EP-3472136-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2019-04-24 | — | — | EP | disclosed |
| WO-2017220485-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190223441-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | PRF1, NOX3, NOX1 | TSHR 2867/4885ALDH1A1 408/4885MEN1 3645/4885 |
| US-11026427-B2 | Microbiocidal oxadiazole derivatives | PRF1, NOX3, NOX1 | TSHR 2867/4885ALDH1A1 408/4885MEN1 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.