Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.54 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921479 | 0.88 | F2 (0.58) | HPGDNPC1RAB9ASMN1; SMN2F2 | |
| SCHEMBL29085939 | 0.85 | AKR1C3 (0.49) | HPGDNPC1RAB9ASMN1; SMN2F2 | |
| SCHEMBL12738664 | 0.84 | NPC1 (0.55) | HPGDNPC1RAB9ASMN1; SMN2F2 | |
| SCHEMBL7962444 | 0.84 | HPGD (0.56) | HPGDNPC1RAB9ASMN1; SMN2F2 | |
| SCHEMBL7962440 | 0.84 | HPGD (0.56) | HPGDNPC1RAB9ASMN1; SMN2F2 | |
| SCHEMBL6373010 | 0.84 | HPGD (0.56) | HPGDNPC1RAB9ASMN1; SMN2F2 | |
| SCHEMBL3858317 | 0.84 | RAB9A (0.50) | HPGDRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6246976 | 0.83 | HPGD (0.55) | HPGDNPC1RAB9ASMN1; SMN2F2 | |
| SCHEMBL19734616 | 0.83 | NPC1 (0.57) | HPGDNPC1RAB9ASMN1; SMN2F2 | |
| SCHEMBL14168120 | 0.83 | NPC1 (0.57) | HPGDNPC1RAB9ASMN1; SMN2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013759-A | Phenylacetic acid amide or thioamide derivatives | THE PROCTER & GAMBLE COMPANY (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0206609-A1 | Compounds and compositions having anti-inflammatory and analgesic activity | THE PROCTER & GAMBLE COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |