Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808658 | 0.91 | TSHR (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL354333 | 0.79 | THRB (0.54) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL1991763 | 0.79 | THRB (0.70) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2742411 | 0.79 | THRB (0.70) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL14706828 | 0.77 | THRB (0.68) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9464153 | 0.77 | THRB (0.68) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5959895 | 0.77 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL672102 | 0.77 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL7157722 | 0.77 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9485961 | 0.77 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077362-A | Thin film coatings | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-12-31 | — | — | US | claimed |
| US-5077362-A | Thin film coatings | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0390078-A1 | Vinylidene fluoride copolymer and process for producing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1990-10-03 | — | — | EP | disclosed |