Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808924 | 0.86 | TSHR (0.35) | ALDH1A1ABL1NPC1CYP1A1 | |
| SCHEMBL9808951 | 0.81 | TDP1 (0.55) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9808963 | 0.80 | TSHR (0.48) | MEN1KMT2ATDP1ALDH1A1KCNH2 | |
| SCHEMBL9808893 | 0.80 | TDP1 (0.48) | MEN1KMT2ATDP1ALDH1A1NPC1 | |
| SCHEMBL9808954 | 0.76 | CYP3A4 (0.41) | MEN1KMT2ATDP1ALDH1A1NPC1 | |
| SCHEMBL9808897 | 0.76 | MEN1 (0.38) | MEN1KMT2ATDP1KCNH2 | |
| SCHEMBL4131774 | 0.75 | MAP2K4 (0.39) | ALDH1A1 | |
| SCHEMBL29655028 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2ATDP1ALDH1A1CYP1A1 | |
| SCHEMBL28012264 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2ATDP1ALDH1A1CYP1A1 | |
| SCHEMBL4048618 | 0.69 | TDP1 (0.70) | MEN1KMT2ATDP1ALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |