Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 3/20 | 0.42 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27652680 | 0.80 | HSD17B10 (0.58) | HSD17B10VCAM1PTPRCS100A4PTGS2 | |
| SCHEMBL10505466 | 0.79 | HSD17B10 (0.45) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL1576857 | 0.75 | ALDH1A1 (0.52) | HSD17B10KMT2AALDH1A1TDP1MEN1 | |
| SCHEMBL9808930 | 0.75 | HSD17B10 (0.51) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL9808964 | 0.74 | HSD17B10 (0.50) | HSD17B10VCAM1PTPRCS100A4KMT2A | |
| SCHEMBL1241730 | 0.74 | FFAR4 (0.48) | HSD17B10VCAM1KMT2AALDH1A1MEN1 | |
| SCHEMBL9808975 | 0.73 | CYP3A4 (0.42) | HSD17B10KMT2AALDH1A1CYP3A4KDM4E | |
| SCHEMBL10452388 | 0.73 | HSD17B10 (0.49) | HSD17B10VCAM1PTPRCS100A4KMT2A | |
| SCHEMBL9808985 | 0.72 | HSD17B10 (0.51) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL21020739 | 0.72 | MAPT (0.48) | HSD17B10VCAM1PTGS2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |