Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808938 | 0.85 | ALDH1A1 (0.50) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9808906 | 0.83 | TSHR (0.60) | MAPTKMT2ATDP1MEN1POLB | |
| SCHEMBL9808954 | 0.83 | CYP3A4 (0.41) | MAPTKMT2ATDP1MEN1ALDH1A1 | |
| SCHEMBL9808937 | 0.81 | MAPT (0.55) | MAPTKMT2ATDP1MEN1POLB | |
| SCHEMBL29655083 | 0.81 | TDP1 (0.55) | MAPTKMT2ATDP1MEN1POLB | |
| SCHEMBL10452550 | 0.81 | TDP1 (0.55) | MAPTKMT2ATDP1MEN1POLB | |
| SCHEMBL9808951 | 0.81 | TDP1 (0.55) | MAPTKMT2ATDP1MEN1POLB | |
| SCHEMBL9808928 | 0.80 | MAPT (0.51) | MAPTKMT2ATDP1MEN1POLB | |
| SCHEMBL717794 | 0.80 | MAPT (0.71) | MAPTKMT2ATDP1MEN1POLB | |
| SCHEMBL29655119 | 0.80 | MAPT (0.54) | MAPTKMT2ATDP1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4956007-A | Nitraminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYOR RT. (HU) | 1990-09-11 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |