Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400570 | 0.87 | KDM4E (0.31) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL10386576 | 0.87 | KDM4E (0.31) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL19445296 | 0.83 | HSD17B10 (0.31) | — | |
| SCHEMBL31034546 | 0.78 | CA12 (0.54) | — | |
| SCHEMBL6454800 | 0.72 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL14614173 | 0.69 | KDM4E (0.59) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL6044950 | 0.69 | MAPT (0.38) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL578641 | 0.66 | PYCR1 (0.39) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL17193567 | 0.66 | HSD17B10 (0.37) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL22349469 | 0.65 | KDM4E (0.36) | MAPTALDH1A1KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117020-B1 | METHOD OF PREPARING TETRAHALOBENZENE COMPOUNDS, CHEMICAL INTERMEDIATES USED THEREIN AND CERTAIN OF THE COMPOUNDS THEMSELVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-22 | — | — | EP | disclosed |
| US-4550206-A | Method of preparing tetrahalobenzene compounds, chemical intermediates used therein and certain of the compounds themselves | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1985-10-29 | — | — | US | disclosed |
| US-4492617-A | Method of preparing tetrahalobenzene compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-08 | — | — | US | disclosed |
| EP-0117020-A2 | Method of preparing tetrahalobenzene compounds, chemical intermediates used therein and certain of the compounds themselves | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-29 | — | — | EP | disclosed |