Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809069 | 0.86 | ALOX15 (0.58) | ALOX15ALDH1A1BCHEPTGS2LMNA | |
| SCHEMBL9809075 | 0.83 | BCHE (0.47) | ALOX15ALDH1A1BCHEPTGS2LMNA | |
| SCHEMBL9809077 | 0.82 | ALOX15 (0.54) | ALOX15ALDH1A1BCHEPTGS2LMNA | |
| SCHEMBL9809087 | 0.82 | ALOX15 (0.58) | ALOX15ALDH1A1BCHEPTGS2LMNA | |
| SCHEMBL9809082 | 0.82 | ALOX15 (0.54) | ALOX15ALDH1A1BCHEPTGS2LMNA | |
| SCHEMBL3882745 | 0.82 | CYP19A1 (0.56) | ALOX15ALDH1A1BCHEPTGS2LMNA | |
| SCHEMBL536896 | 0.81 | CYP19A1 (0.55) | ALOX15ALDH1A1BCHEPTGS2LMNA | |
| SCHEMBL588715 | 0.79 | ALDH1A1 (0.68) | ALOX15ALDH1A1BCHEPTGS2LMNA | |
| SCHEMBL2449608 | 0.79 | ALOX15 (0.68) | ALOX15ALDH1A1BCHEPTGS2LMNA | |
| SCHEMBL9809118 | 0.78 | POLB (0.42) | ALOX15ALDH1A1BCHEPTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |