Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809125 | 0.88 | CYP19A1 (0.44) | CYP19A1BCHEFPR2MAOAMAOB | |
| SCHEMBL3882745 | 0.85 | CYP19A1 (0.56) | CYP19A1BCHEMAOAMAOBALDH1A1 | |
| SCHEMBL536896 | 0.84 | CYP19A1 (0.55) | CYP19A1BCHEMAOAMAOBALDH1A1 | |
| SCHEMBL9809075 | 0.83 | BCHE (0.47) | BCHEFPR2ALDH1A1ALOX15PTGS2 | |
| SCHEMBL9809079 | 0.81 | BCHE (0.45) | BCHEFPR2ALDH1A1ALOX15PTGS2 | |
| SCHEMBL9809064 | 0.76 | NOX4 (0.45) | CYP19A1BCHEFPR2MAOAMAOB | |
| SCHEMBL9809062 | 0.74 | CYP19A1 (0.38) | CYP19A1BCHEMAOAMAOBALDH1A1 | |
| SCHEMBL9809100 | 0.70 | MAPT (0.38) | CYP19A1MAOAMAOBALDH1A1GAA | |
| SCHEMBL9809063 | 0.70 | BCHE (0.49) | CYP19A1BCHEMAOAMAOBALDH1A1 | |
| SCHEMBL9809111 | 0.69 | CYP19A1 (0.37) | CYP19A1MAOAMAOBALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |